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Enzyme dynamics point to stepwise conformational selection in catalysis

Recent data increasingly reveal that conformational dynamics are indispensable to enzyme function throughout the catalytic cycle, in substrate recruiting, chemical transformation, and product release. Conformational transitions may involve conformational selection and induced fit, which can be viewe...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: Ma, Buyong, Nussinov, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407632/
https://ncbi.nlm.nih.gov/pubmed/20822947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.08.012
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