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Enzyme dynamics point to stepwise conformational selection in catalysis

Recent data increasingly reveal that conformational dynamics are indispensable to enzyme function throughout the catalytic cycle, in substrate recruiting, chemical transformation, and product release. Conformational transitions may involve conformational selection and induced fit, which can be viewe...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Chem Biol
Hauptverfasser: Ma, Buyong, Nussinov, Ruth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407632/
https://ncbi.nlm.nih.gov/pubmed/20822947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.08.012
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