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Dynamic energy landscape view of coupled binding and protein conformational change: Induced-fit versus population-shift mechanisms
Allostery, the coupling between ligand binding and protein conformational change, is the heart of biological network and it has often been explained by two representative models, the induced-fit and the population-shift models. Here, we clarified for what systems one model fits better than the other...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516237/ https://ncbi.nlm.nih.gov/pubmed/18678900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802524105 |
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