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Energy landscape views for interplays among folding, binding, and allostery of calmodulin domains
Ligand binding modulates the energy landscape of proteins, thus altering their folding and allosteric conformational dynamics. To investigate such interplay, calmodulin has been a model protein. Despite much attention, fully resolved mechanisms of calmodulin folding/binding have not been elucidated....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4115553/ https://ncbi.nlm.nih.gov/pubmed/25002491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402768111 |
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