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Energy landscape views for interplays among folding, binding, and allostery of calmodulin domains

Ligand binding modulates the energy landscape of proteins, thus altering their folding and allosteric conformational dynamics. To investigate such interplay, calmodulin has been a model protein. Despite much attention, fully resolved mechanisms of calmodulin folding/binding have not been elucidated....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Wenfei, Wang, Wei, Takada, Shoji
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115553/
https://ncbi.nlm.nih.gov/pubmed/25002491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402768111
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