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Nucleosome allostery in pioneer transcription factor binding
While recent experiments revealed that some pioneer transcription factors (TFs) can bind to their target DNA sequences inside a nucleosome, the binding dynamics of their target recognitions are poorly understood. Here we used the latest coarse-grained models and molecular dynamics simulations to stu...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7456188/ https://ncbi.nlm.nih.gov/pubmed/32778600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005500117 |
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