Defining transcription factor nucleosome binding with Pioneer-seq.
Gene expression requires the targeting of transcription factors (TFs) to regulatory sequences often occluded within nucleosomes. To comprehensively examine TF nucleosome binding, we developed Pioneer-Seq. In Pioneer-seq a library of thousands of nucleosomes are formed from sequences containing a TF...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2025-08-01
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| Colección: | PLoS Genetics |
| Acceso en línea: | https://doi.org/10.1371/journal.pgen.1011813 |
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