Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation
Abstract Pioneer transcription factors (TF) bind nucleosome-embedded DNA motifs to activate new regulatory elements and promote differentiation. However, the complexity, binding dependencies and temporal effects of their action remain unclear. Here, we dissect how ectopic induction of the pioneer TF...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2025-12-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-025-67308-0 |
| Etykiety: |
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