Overexpression of Fto leads to increased food intake and results in obesity

Genome-wide association studies have identified SNPs within the human FTO gene that display a strong association with obesity. Individuals homozygous for the at-risk rs9939609 A allele weigh ~3kg more. Loss of function and/or expression of FTO in mice leads to increased energy expenditure and a lean...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Church, Chris, Moir, Lee, McMurray, Fiona, Girard, Christophe, Banks, Gareth T, Teboul, Lydia, Wells, Sara, Bruning, Jens C., Nolan, Patrick M, Ashcroft, Frances M., Cox, Roger D.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018646/
https://ncbi.nlm.nih.gov/pubmed/21076408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.713
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires