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FTO demethylase activity is essential for normal bone growth and bone mineralization in mice
The Fto gene locus has been linked to increased body weight and obesity in human population studies, but the role of the actual FTO protein in adiposity has remained controversial. Complete loss of FTO protein in mouse and of FTO function in human patients has multiple and variable effects. To deter...
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| Publicado no: | Biochim Biophys Acta |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Pub. Co
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798602/ https://ncbi.nlm.nih.gov/pubmed/29203346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.11.027 |
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