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Brief Ampakine Treatments Slow the Progression of Huntington’s Disease Phenotypes in R6/2 Mice
Daily, systemic injections of a positive AMPA-type glutamate receptor modulator (ampakine) have been shown to reduce synaptic plasticity defects in rodent models of aging and early-stage Huntington’s Disease (HD). Here we report that long-term ampakine treatment markedly slows the progression of str...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014441/ https://ncbi.nlm.nih.gov/pubmed/20977939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.10.015 |
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