Ampakines cause sustained increases in BDNF signaling at excitatory synapses without changes in AMPA receptor subunit expression

Recent demonstrations that positive modulators of AMPA-type glutamate receptors (ampakines) increase neuronal brain-derived neurotrophic factor (BDNF) expression have suggested a novel strategy for treating neurodegenerative diseases. However, reports that AMPA and BDNF receptors are down-regulated...

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Autori principali: Lauterborn, Julie C., Pineda, Eduardo, Chen, Lulu Y., Ramirez, Eduardo A., Lynch, Gary, Gall, Christine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746455/
https://ncbi.nlm.nih.gov/pubmed/19141314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.12.018
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