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Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice
Cognitive problems occur in asymptomatic gene carriers of Huntington's disease (HD), and mouse models of the disease exhibit impaired learning and substantial deficits in the cytoskeletal changes that stabilize long-term potentiation (LTP). The latter effects may be related to the decreased pro...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660722/ https://ncbi.nlm.nih.gov/pubmed/19264961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811228106 |
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