Chronic Ampakine Treatments Stimulate Dendritic Growth and Promote Learning in Middle-Aged Rats

Positive allosteric modulators of AMPA-type glutamate receptors (ampakines) have been shown to rescue synaptic plasticity and reduce neuropathology in rodent models of cognitive disorders. Here we tested whether chronic ampakine treatment offsets age-related dendritic retraction in middle-aged (MA)...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lauterborn, Julie C., Palmer, Linda C., Jia, Yousheng, Pham, Danielle T., Hou, Bowen, Wang, Weisheng, Trieu, Brian H., Cox, Conor D., Kantorovich, Svetlana, Gall, Christine M., Lynch, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737774/
https://ncbi.nlm.nih.gov/pubmed/26843645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3157-15.2016
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