SGLT2 Mediates Glucose Reabsorption in the Early Proximal Tubule

Mutations in the gene encoding for the Na(+)-glucose co-transporter SGLT2 (SLC5A2) associate with familial renal glucosuria, but the role of SGLT2 in the kidney is incompletely understood. Here, we determined the localization of SGLT2 in the mouse kidney and generated and characterized SGLT2-deficie...

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Bibliographic Details
Main Authors: Vallon, Volker, Platt, Kenneth A., Cunard, Robyn, Schroth, Jana, Whaley, Jean, Thomson, Scott C., Koepsell, Hermann, Rieg, Timo
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2011
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014039/
https://ncbi.nlm.nih.gov/pubmed/20616166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010030246
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