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Development of SGLT1 and SGLT2 inhibitors

Sodium–glucose cotransporters SGLT1 (encoded by SGLT1, also known as SLC5A1) and SGLT2 (encoded by SGLT2, also known as SLC5A2) are important mediators of epithelial glucose transport. While SGLT1 accounts for most of the dietary glucose uptake in the intestine, SGLT2 is responsible for the majority...

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Dettagli Bibliografici
Pubblicato in:Diabetologia
Autori principali: Rieg, Timo, Vallon, Volker
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124499/
https://ncbi.nlm.nih.gov/pubmed/30132033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4654-7
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