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Development of SGLT1 and SGLT2 inhibitors

Sodium–glucose cotransporters SGLT1 (encoded by SGLT1, also known as SLC5A1) and SGLT2 (encoded by SGLT2, also known as SLC5A2) are important mediators of epithelial glucose transport. While SGLT1 accounts for most of the dietary glucose uptake in the intestine, SGLT2 is responsible for the majority...

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Publicado en:Diabetologia
Autores principales: Rieg, Timo, Vallon, Volker
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124499/
https://ncbi.nlm.nih.gov/pubmed/30132033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4654-7
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