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Development of SGLT1 and SGLT2 inhibitors

Sodium–glucose cotransporters SGLT1 (encoded by SGLT1, also known as SLC5A1) and SGLT2 (encoded by SGLT2, also known as SLC5A2) are important mediators of epithelial glucose transport. While SGLT1 accounts for most of the dietary glucose uptake in the intestine, SGLT2 is responsible for the majority...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Diabetologia
Hauptverfasser: Rieg, Timo, Vallon, Volker
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124499/
https://ncbi.nlm.nih.gov/pubmed/30132033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4654-7
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