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Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition
Healthy kidneys filter ~160 g/day of glucose (~30% of daily energy intake) under euglycaemic conditions. To prevent valuable energy from being lost in the urine, the proximal tubule avidly reabsorbs filtered glucose up to a limit of ~450 g/day. When blood glucose levels increase to the point that th...
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| Pubblicato in: | Diabetologia |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884445/ https://ncbi.nlm.nih.gov/pubmed/27878313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4157-3 |
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