BTBR Ob/Ob Mutant Mice Model Progressive Diabetic Nephropathy

There remains a need for robust mouse models of diabetic nephropathy (DN) that mimic key features of advanced human DN. The recently developed mouse strain BTBR with the ob/ob leptin-deficiency mutation develops severe type 2 diabetes, hypercholesterolemia, elevated triglycerides, and insulin resist...

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Detaylı Bibliyografya
Asıl Yazarlar: Hudkins, Kelly L., Pichaiwong, Warangkana, Wietecha, Tomasz, Kowalewska, Jolanta, Banas, Miriam C., Spencer, Min W., Mühlfeld, Anja, Koelling, Mariko, Pippin, Jeffrey W., Shankland, Stuart J., Askari, Bardia, Rabaglia, Mary E., Keller, Mark P., Attie, Alan D., Alpers, Charles E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2010
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013527/
https://ncbi.nlm.nih.gov/pubmed/20634301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121290
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