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Reversibility of Structural and Functional Damage in a Model of Advanced Diabetic Nephropathy
The reversibility of diabetic nephropathy remains controversial. Here, we tested whether replacing leptin could reverse the advanced diabetic nephropathy modeled by the leptin-deficient BTBR ob/ob mouse. Leptin replacement, but not inhibition of the renin-angiotensin-aldosterone system (RAAS), resul...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Nephrology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699819/ https://ncbi.nlm.nih.gov/pubmed/23641056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050445 |
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