BTBR Ob/Ob Mutant Mice Model Progressive Diabetic Nephropathy

There remains a need for robust mouse models of diabetic nephropathy (DN) that mimic key features of advanced human DN. The recently developed mouse strain BTBR with the ob/ob leptin-deficiency mutation develops severe type 2 diabetes, hypercholesterolemia, elevated triglycerides, and insulin resist...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Hudkins, Kelly L., Pichaiwong, Warangkana, Wietecha, Tomasz, Kowalewska, Jolanta, Banas, Miriam C., Spencer, Min W., Mühlfeld, Anja, Koelling, Mariko, Pippin, Jeffrey W., Shankland, Stuart J., Askari, Bardia, Rabaglia, Mary E., Keller, Mark P., Attie, Alan D., Alpers, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2010
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013527/
https://ncbi.nlm.nih.gov/pubmed/20634301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121290
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares