Loading...
NF-E2- related factor 2 (Nrf2) is a positive regulator of human bile salt export pump (BSEP) expression
The bile salt export pump (BSEP, ABCB11) is the major determinant of bile salt dependent bile secretion and its deficiency leads to cholestatic liver injury. BSEP/Bsep gene expression is regulated by the nuclear farnesoid X receptor (FXR). However, BSEP expression is retained in the liver of the Fxr...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013376/ https://ncbi.nlm.nih.gov/pubmed/19821532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23151 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|