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The Bile Salt Export Pump: Clinical and Experimental Aspects of Genetic and Acquired Cholestatic Liver Disease

The primary transporter responsible for bile salt secretion is the bile salt export pump (BSEP, ABCB11), a member of the ATP-binding cassette (ABC) superfamily, which is located at the bile canalicular apical domain of hepatocytes. In humans, BSEP deficiency results in several different genetic form...

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Detalhes bibliográficos
Main Authors: Lam, Ping, Soroka, Carol J., Boyer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008346/
https://ncbi.nlm.nih.gov/pubmed/20422495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0030-1253222
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