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Biosynthesis and Trafficking of the Bile Salt Export Pump, BSEP: Therapeutic Implications of BSEP Mutations

The bile salt export pump (BSEP, ABCB11) is the primary transporter of bile acids from the hepatocyte to the biliary system. This rate-limiting step in bile formation is essential to the formation of bile salt dependent bile flow, the enterohepatic circulation of bile acids, and the digestion of die...

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Autors principals: Soroka, Carol J., Boyer, James L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784619/
https://ncbi.nlm.nih.gov/pubmed/23685087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2013.05.001
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