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Contributions of distinct quaternary contacts to cooperative operator binding by Mnt repressor

Mnt, a tetrameric repressor encoded by bacteriophage P22, uses N-domain dimers to contact each half of its operator site. Experiments with a double mutant and structural homology with the P22 Arc repressor suggest that contacts made by Arg-28 and stabilized by Glu-33 are largely responsible for dime...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Berggrun, Arie, Sauer, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30133/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226234/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041612198
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