Contributions of distinct quaternary contacts to cooperative operator binding by Mnt repressor
Mnt, a tetrameric repressor encoded by bacteriophage P22, uses N-domain dimers to contact each half of its operator site. Experiments with a double mutant and structural homology with the P22 Arc repressor suggest that contacts made by Arg-28 and stabilized by Glu-33 are largely responsible for dime...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30133/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226234/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041612198 |
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