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Contributions of distinct quaternary contacts to cooperative operator binding by Mnt repressor

Mnt, a tetrameric repressor encoded by bacteriophage P22, uses N-domain dimers to contact each half of its operator site. Experiments with a double mutant and structural homology with the P22 Arc repressor suggest that contacts made by Arg-28 and stabilized by Glu-33 are largely responsible for dime...

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Bibliografski detalji
Glavni autori: Berggrun, Arie, Sauer, Robert T.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC30133/
https://ncbi.nlm.nih.gov/pubmed/11226234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041612198
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