Prostaglandin E(2) Activates and Utilizes mTORC2 as a Central Signaling Locus for the Regulation of Mast Cell Chemotaxis and Mediator Release

Prostaglandin (PG) E(2), a potent mediator produced in inflamed tissues, can substantially influence mast cell responses including adhesion to basement membrane proteins, chemotaxis, and chemokine production. However, the signaling pathways by which PGE(2) induces mast cell chemotaxis and chemokine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kuehn, Hye Sun, Jung, Mi-Yeon, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012997/
https://ncbi.nlm.nih.gov/pubmed/20980255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164772
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