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Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells

Following antigen/IgE-mediated aggregation of high affinity IgE-receptors (FcεRI), mast cells (MCs) degranulate and release inflammatory mediators leading to the induction of allergic reactions including anaphylaxis. Migration of MCs to resident tissues and sites of inflammation is regulated by tiss...

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Detaylı Bibliyografya
Asıl Yazarlar: Smrž, Daniel, Bandara, Geethani, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798040/
https://ncbi.nlm.nih.gov/pubmed/23616175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243214
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