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Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells

Following antigen/IgE-mediated aggregation of high affinity IgE-receptors (FcεRI), mast cells (MCs) degranulate and release inflammatory mediators leading to the induction of allergic reactions including anaphylaxis. Migration of MCs to resident tissues and sites of inflammation is regulated by tiss...

詳細記述

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書誌詳細
主要な著者: Smrž, Daniel, Bandara, Geethani, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798040/
https://ncbi.nlm.nih.gov/pubmed/23616175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243214
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