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Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells

Following antigen/IgE-mediated aggregation of high affinity IgE-receptors (FcεRI), mast cells (MCs) degranulate and release inflammatory mediators leading to the induction of allergic reactions including anaphylaxis. Migration of MCs to resident tissues and sites of inflammation is regulated by tiss...

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Bibliografische gegevens
Hoofdauteurs: Smrž, Daniel, Bandara, Geethani, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798040/
https://ncbi.nlm.nih.gov/pubmed/23616175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243214
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