Llwytho...

t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL

The most frequent MLL-gene rearrangement found in leukemia is a reciprocal translocation with AF4 on chromosome 4 resulting in the formation of the MLL-AF4 and the AF4-MLL fusion genes. The oncogenic role of MLL-AF4 is documented but the significance of the reciprocal product - AF4-MLL in leukemia i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kumar, Ashish R., Yao, Qing, Li, Quanzhi, Sam, Thien A., Kersey, John H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011030/
https://ncbi.nlm.nih.gov/pubmed/20869771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2010.08.011
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