Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.

A chromosomal translocation, t(4;11)-(q21;q23), is associated with an aggressive mixed-lineage leukemia. A yeast artificial chromosome was used to clone the chromosomal breakpoint of this translocation in the RS4;11 cell line. The breakpoint sequences revealed an inverted repeat bordered by a consen...

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Detalhes bibliográficos
Main Authors: Domer, P H, Fakharzadeh, S S, Chen, C S, Jockel, J, Johansen, L, Silverman, G A, Kersey, J H, Korsmeyer, S J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47247/
https://ncbi.nlm.nih.gov/pubmed/7689231
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