Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.
A chromosomal translocation, t(4;11)-(q21;q23), is associated with an aggressive mixed-lineage leukemia. A yeast artificial chromosome was used to clone the chromosomal breakpoint of this translocation in the RS4;11 cell line. The breakpoint sequences revealed an inverted repeat bordered by a consen...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7689231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7884 |
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