Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.

A chromosomal translocation, t(4;11)-(q21;q23), is associated with an aggressive mixed-lineage leukemia. A yeast artificial chromosome was used to clone the chromosomal breakpoint of this translocation in the RS4;11 cell line. The breakpoint sequences revealed an inverted repeat bordered by a consen...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Domer, P H, Fakharzadeh, S S, Chen, C S, Jockel, J, Johansen, L, Silverman, G A, Kersey, J H, Korsmeyer, S J
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7689231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7884
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