A role for MEIS1 in MLL-fusion gene leukemia

Leukemias with MLL rearrangements are characterized by high expression of the homeobox gene MEIS1. In these studies, we knocked down Meis1 expression by shRNA lentivirus transduction in murine Mll-AF9 leukemia cells. Meis1 knockdown resulted in decreased proliferation and survival of murine Mll-AF9...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kumar, Ashish R., Li, Quanzhi, Hudson, Wendy A., Chen, Weili, Sam, Thien, Yao, Qing, Lund, Erik A., Wu, Baolin, Kowal, Branden J., Kersey, John H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2009
Pynciau:
Myeloid Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647665/
https://ncbi.nlm.nih.gov/pubmed/19109563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-163287
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