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Two-dimensional liquid chromatography system for online top-down mass spectrometry
An online metal-free weak cation exchange-hydrophilic interaction LC/RPLC system has been developed for sensitive, high-throughput top-down MS. Here, we report results for analyzing PTMs of core histones, with a focus on histone H4, using this system. With just ~24 μg on-column of core histones (H4,...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010896/ https://ncbi.nlm.nih.gov/pubmed/20879039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000367 |
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