Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci

Glycogen synthase kinase-3 (Gsk-3) isoforms, Gsk-3α and Gsk-3β, are constitutively active, largely inhibitory kinases involved in signal transduction. Underscoring their biological significance, altered Gsk-3 activity has been implicated in diabetes, Alzheimer disease, schizophrenia, and bipolar dis...

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Detaylı Bibliyografya
Asıl Yazarlar: Popkie, Anthony P., Zeidner, Leigh C., Albrecht, Ashley M., D'Ippolito, Anthony, Eckardt, Sigrid, Newsom, David E., Groden, Joanna, Doble, Bradley W., Aronow, Bruce, McLaughlin, K. John, White, Peter, Phiel, Christopher J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009859/
https://ncbi.nlm.nih.gov/pubmed/21047779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170704
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