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A Noncatalytic Domain of Glycogen Synthase Kinase-3 (GSK-3) Is Essential for Activity

Glycogen synthase kinase-3 (GSK-3) isoforms, GSK-3α and GSK-3β, are serine/threonine kinases involved in numerous cellular processes and diverse diseases, including Alzheimer disease, cancer, and diabetes. GSK-3 isoforms function redundantly in some settings, while, in others, they exhibit distinct...

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Detalhes bibliográficos
Main Authors: Buescher, Jessica L., Phiel, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832946/
https://ncbi.nlm.nih.gov/pubmed/20080974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091603
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