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A Noncatalytic Domain of Glycogen Synthase Kinase-3 (GSK-3) Is Essential for Activity

Glycogen synthase kinase-3 (GSK-3) isoforms, GSK-3α and GSK-3β, are serine/threonine kinases involved in numerous cellular processes and diverse diseases, including Alzheimer disease, cancer, and diabetes. GSK-3 isoforms function redundantly in some settings, while, in others, they exhibit distinct...

詳細記述

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書誌詳細
主要な著者: Buescher, Jessica L., Phiel, Christopher J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832946/
https://ncbi.nlm.nih.gov/pubmed/20080974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091603
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