Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci

Glycogen synthase kinase-3 (Gsk-3) isoforms, Gsk-3α and Gsk-3β, are constitutively active, largely inhibitory kinases involved in signal transduction. Underscoring their biological significance, altered Gsk-3 activity has been implicated in diabetes, Alzheimer disease, schizophrenia, and bipolar dis...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Popkie, Anthony P., Zeidner, Leigh C., Albrecht, Ashley M., D'Ippolito, Anthony, Eckardt, Sigrid, Newsom, David E., Groden, Joanna, Doble, Bradley W., Aronow, Bruce, McLaughlin, K. John, White, Peter, Phiel, Christopher J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009859/
https://ncbi.nlm.nih.gov/pubmed/21047779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170704
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы