Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells

Glycogen synthase kinase-3 (GSK-3) activity regulates multiple signal transduction pathways and is also a key component of the network responsible for maintaining stem cell pluripotency. Genetic deletion of Gsk-3α and Gsk-3β or inhibition of GSK-3 activity via small molecules promotes stem cell plur...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Faulds, Kelsie J., Egelston, Jennifer N., Sedivy, Laura J., Mitchell, Matthew K., Garimella, Sanjana, Kozlowski, Hanna, D'Alessandro, Angelo, Hansen, Kirk C., Balsbaugh, Jeremy L., Phiel, Christopher J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036209/
https://ncbi.nlm.nih.gov/pubmed/29777057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001298
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