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DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

We hypothesized that DNA methylation distributes into specific patterns in cancer cells, which reflect critical biological differences. We therefore examined the methylation profiles of 344 patients with acute myeloid leukemia (AML). Clustering of these patients by methylation data segregated patien...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Figueroa, Maria E., Lugthart, Sanne, Li, Yushan, Erpelinck-Verschueren, Claudia, Deng, Xutao, Christos, Paul J., Schifano, Elizabeth, Booth, James, van Putten, Wim, Skrabanek, Lucy, Campagne, Fabien, Mazumdar, Madhu, Greally, John M., Valk, Peter J.M., Löwenberg, Bob, Delwel, Ruud, Melnick, Ari
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008568/
https://ncbi.nlm.nih.gov/pubmed/20060365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.11.020
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