DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

We hypothesized that DNA methylation distributes into specific patterns in cancer cells, which reflect critical biological differences. We therefore examined the methylation profiles of 344 patients with acute myeloid leukemia (AML). Clustering of these patients by methylation data segregated patien...

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Bibliografiset tiedot
Päätekijät: Figueroa, Maria E., Lugthart, Sanne, Li, Yushan, Erpelinck-Verschueren, Claudia, Deng, Xutao, Christos, Paul J., Schifano, Elizabeth, Booth, James, van Putten, Wim, Skrabanek, Lucy, Campagne, Fabien, Mazumdar, Madhu, Greally, John M., Valk, Peter J.M., Löwenberg, Bob, Delwel, Ruud, Melnick, Ari
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008568/
https://ncbi.nlm.nih.gov/pubmed/20060365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.11.020
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