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XLF regulates filament architecture of the XRCC4·Ligase IV complex
DNA ligase IV (LigIV) is critical for non-homologous end-joining (NHEJ), the major DNA double-strand break (DSB) repair pathway in human cells, and LigIV activity is regulated by XRCC4 and XLF (XRCC4-like factor) interactions. Here, we employ X-ray scattering (SAXS) data to characterize three-dimens...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008546/ https://ncbi.nlm.nih.gov/pubmed/21070942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.09.009 |
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