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Hsp90 modulates CAG repeat instability in human cells

The Hsp90 molecular chaperone has been implicated as a contributor to evolution in several organisms by revealing cryptic variation that can yield dramatic phenotypes when the chaperone is diverted from its normal functions by environmental stress. In addition, as a cancer drug target, Hsp90 inhibit...

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Библиографические подробности
Главные авторы: Mittelman, David, Sykoudis, Kristen, Hersh, Megan, Lin, Yunfu, Wilson, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006633/
https://ncbi.nlm.nih.gov/pubmed/20373063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-010-0191-0
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