A carregar...
R loops stimulate genetic instability of CTG·CAG repeats
Transcription stimulates the genetic instability of trinucleotide repeat sequences. However, the mechanisms leading to transcription-dependent repeat length variation are unclear. We demonstrate, using biochemical and genetic approaches, that the formation of stable RNA·DNA hybrids enhances the inst...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818888/ https://ncbi.nlm.nih.gov/pubmed/20080737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909740107 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|