Inhibitors of Foot and Mouth Disease Virus Targeting a Novel Pocket of the RNA-Dependent RNA Polymerase

BACKGROUND: Foot-and-Mouth Disease Virus (FMDV) is a picornavirus that infects cloven-hoofed animals and leads to severe losses in livestock production. In the case of an FMD outbreak, emergency vaccination requires at least 7 days to trigger an effective immune response. There are currently no appr...

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Detalhes bibliográficos
Main Authors: Durk, Ryan C., Singh, Kamalendra, Cornelison, Ceili A., Rai, Devendra K., Matzek, Kayla B., Leslie, Maxwell D., Schafer, Elizabeth, Marchand, Bruno, Adedeji, Adeyemi, Michailidis, Eleftherios, Dorst, Christopher A., Moran, Jennifer, Pautler, Christie, Rodriguez, Luis L., McIntosh, Mark A., Rieder, Elizabeth, Sarafianos, Stefan G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006429/
https://ncbi.nlm.nih.gov/pubmed/21203539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015049
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