Nalaganje...

Activation of the NLRP3 inflammasome by intracellular poly I:C

Several RNA viruses can be detected by the inflammasome, which promotes IL-1β and IL-18 secretion, but the underlying mechanisms of detection remain unclear. Cytosolic dsRNA is a replication intermediate of many RNA viruses. We show here that transfection of the dsRNA analogue poly I:C activates the...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Rajan, Jayant V., Warren, Sarah E., Miao, Edward A., Aderem, Alan
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005299/
https://ncbi.nlm.nih.gov/pubmed/20971108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.10.036
Oznake: Označite
Brez oznak, prvi označite!