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The NLRP3 Inflammasome Detects Encephalomyocarditis Virus and Vesicular Stomatitis Virus Infection

Inflammasomes are cytosolic protein complexes that regulate caspase-1 activation and the secretion of interleukin-1β (IL-1β) and IL-18. Several different inflammasome complexes have been identified, but the NLRP3 inflammasome is particularly notable because of its central role in diseases of inflamm...

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Detalhes bibliográficos
Main Authors: Rajan, Jayant V., Rodriguez, David, Miao, Edward A., Aderem, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126243/
https://ncbi.nlm.nih.gov/pubmed/21289120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01687-10
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