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The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation

Inhibition of eukaryotic DNA replication leads to the rapid suppression of histone synthesis, via 3′ uridylation of cytoplasmic histone mRNAs followed by their Lsm1–7-mediated decapping and degradation. Here we show that the human cytoplasmic RNA terminal U-transferase ZCCHC11, recently implicated i...

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Bibliografische gegevens
Hoofdauteurs: Schmidt, Marie-Joëlle, West, Steven, Norbury, Chris J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004064/
https://ncbi.nlm.nih.gov/pubmed/21051505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2252511
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