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The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation
Inhibition of eukaryotic DNA replication leads to the rapid suppression of histone synthesis, via 3′ uridylation of cytoplasmic histone mRNAs followed by their Lsm1–7-mediated decapping and degradation. Here we show that the human cytoplasmic RNA terminal U-transferase ZCCHC11, recently implicated i...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3004064/ https://ncbi.nlm.nih.gov/pubmed/21051505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2252511 |
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