Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase

Cytoplasmic terminal uridylyltransferases (TUTases) comprise a conserved family of enzymes that negatively regulate the stability or biological activity of a variety of eukaryotic RNAs, including mRNAs and tumor suppressor let-7 miRNAs. Here we describe crystal structures of the Schizosaccharomyces...

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Détails bibliographiques
Publié dans:Nat Struct Mol Biol
Auteurs principaux: Yates, Luke A., Fleurdépine, Sophie, Rissland, Olivia S., De Colibus, Luigi, Harlos, Karl, Norbury, Chris J., Gilbert, Robert J. C.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342108/
https://ncbi.nlm.nih.gov/pubmed/22751018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2329
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