A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues

Histone proteins are synthesized in large amounts during S-phase to package the newly replicated DNA, and are among the most stable proteins in the cell. The replication-dependent (RD)-histone mRNAs expressed during S-phase end in a conserved stem-loop rather than a polyA tail. In addition, there ar...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Lyons, Shawn M., Cunningham, Clark H., Welch, Joshua D., Groh, Beezly, Guo, Andrew Y., Wei, Bruce, Whitfield, Michael L., Xiong, Yue, Marzluff, William F.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Gene regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100578/
https://ncbi.nlm.nih.gov/pubmed/27402160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw620
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