טוען...
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) in DNA1,2. The gene encoding TET2 resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of heterozygosity (CN-LOH) in patients with diverse my...
שמור ב:
Main Authors: | , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
2010
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003755/ https://ncbi.nlm.nih.gov/pubmed/21057493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09586 |
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